Inhibition by dicyclohexylcarbodiimide of proton ejection but not electron transfer in rat liver mitochondria.
نویسندگان
چکیده
منابع مشابه
Inhibition of Electron and Energy Transfer in Mitochondria
The inhibition by oxybarbiturates of diphosphopyridine nucleotide (DPN)-linked oxidations in mitochondria was observed some time ago (l-4). Their effect on the associated phosphorylation was subsequently reported (5,6), but it is now apparent that oxybarbiturates do not uncouple oxidative phosphorylation (7) nor do they inhibit dinitrophenol-activated adenosine triphosphatase (7). Amytal inhibi...
متن کاملProton movements and adenosine triphosphate synthesis in rat liver mitochondria.
In a previous communication (Archbold et al., 1974) we have described experiments the results of which are not readily reconciled with some aspects of the chemiosmotic hypothesis. Our interpretation required a distinction between the distributive nature ofelectroneutral (EN) and eiectrogenic (EG) proton movements across the mitochondria1 inner membrane. This distinction has not been made hither...
متن کاملSTUDY OF MITOCHONDRIA IN RAT LIVER Quantitative Electron Microscopy
The electron microscope has been used to determine the weight distribution of isolated subcellular particles from normal rat liver. The following results are reported: (1) There exist at least two well defined weight populations of subcellular particles; their respective median weights are 1.3 X l0 -j4 and l l X l0 u gm. The lighter fraction is considered to consist of lysosomes, the heavier of...
متن کاملSTUDY OF MITOCHONDRIA IN RAT LIVER Quantitative Electron Microscopy
The electron microscope has been used to determine the weight distribution of isolated subcellular particles from normal rat liver. The following results are reported: (1) There exist at least two well defined weight populations of subcellular particles; their respective median weights are 1.3 X l0 -j4 and l l X l0 u gm. The lighter fraction is considered to consist of lysosomes, the heavier of...
متن کاملSTUDY OF MITOCHONDRIA IN RAT LIVER Quantitative Electron Microscopy
The electron microscope has been used to determine the weight distribution of isolated subcellular particles from normal rat liver. The following results are reported: (1) There exist at least two well defined weight populations of subcellular particles; their respective median weights are 1.3 X l0 -j4 and l l X l0 u gm. The lighter fraction is considered to consist of lysosomes, the heavier of...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1984
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)90649-6